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During Years 1 and 2, students enroll in four sequential semesters of Integrated Medical Sciences (IMS) and Doctoring. The elective Scholarly Concentration Program is introduced to students during Year 1.

IMS-I provides first-year medical students with foundations of cell biology, cell physiology, biochemistry, nutrition sciences, immunology, genetics, and introductory pharmacology, all of which are integrated with gross and microscopic anatomy. IMS-I also includes general pathology, in which students are introduced to concepts underlying the mechanisms of disease.  Finally, the health systems science course considers broader concepts of health—including environmental and social issues with a focus on health disparities—as well as epidemiology.

Brain Sciences, the first course of IMS-II, integrates head and neck anatomy with neurobiology, brain and behavior, neurologic pathology, neuropathophysiology, and neuropharmacology.  The second IMS-II course integrates musculoskeletal anatomy with an introduction to the fields of orthopedics, rheumatology, and dermatology. The first year ends with a course that integrates microbiology with infectious diseases and relevant pharmacology.

Students continue with a systems-based approach in Year 2, which includes the following courses: cardiovascular, renal, pulmonary, endocrinology, human reproduction, hematology, and gastroenterology. Each systems-based course includes the relevant physiology, pathophysiology, pathology, and pharmacology organized in an integrated fashion. In addition, students have self-directed learning time in the second-year schedule to accommodate participation in scholarly activities.